Keyword cytochrome 450 in mushrooms

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February'12


In this issue, Dr. Stoyan Borisov presents his clinical assessment study on the effect of Coriolus versicolor supplementation on patients with Low-risk and High-risk HPV subtypes. Dr. Chris Newton (Ph.D) proposes a study on the potential role of mushroom nutrition as modulators of toll receptor-mediated immune response.

The enzyme researcher, Dr. Amin Karmali (Ph.D) presents a detoxification analysis (in vitro) on mushroom nutrition, outlining the superoxide dismutase activity, cytochrome P450, cytochrome P450 reductase and secondary metabolites activity of Grifola frondosa (Maitake), Ganoderma lucidum (Reishi), Coriolus versicolor and Cordyceps sinensis.

Finally, the latest poster presentation on the efficacy of Coriolus versicolor in the treatment of HPV lesions (LSIL), presented by Dr. J.Silva Couto at the 14th World Congress of Cervical Pathology and Colpscopy- (IFCPC)-July 4th to 7th, 2011 in Rio de Janeiro, Brasil.

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March'07


The Clinical Journal of Mycology (formerly Mycology News) is dedicated to the dissemination of information on the clinical use of mushroom nutrition to health care practitioners. In this issue we address the role of Coriolus versicolor in the treatment of CIN-1 (LSIL HPV) and Herpes Simplex.

Dr J Silva Couto outlines the difference between LSIL and HSIL HPV and provides a protocol for use by medical professionals. In addition, Prof Amin Karmali explains the enzymatic qualities of Coriolus versicolor and how such attributes assist the immune system. Finally, Dr. Andrew French outlines his clinical experience using Coriolus versicolor in patients with herpes simplex with a recommended protocol for consultants.

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September'05

In this edition, Dr Rajendra Sharma presents the results of 13 patient study on the use of Coriolus-MRL supplementation (4,5 g day over 90 days) in Leaky Gut Syndrome. Dr Jean Monro outlines a prospective trial design for HPV control with Coriolus versicolor. A prostate cancer case study is outlined in which the patient, Gary Bates, describes his experience taking Coriolus versicolor an Cordyceps sinensis supplementation while undergoing hormone blocking treatment. Dr Girao Bastos outlines the use of Coriolus supplementation in a dog with prostate cancer. The TCM lecturer, John Tindall, provides a protocol on the use of Reishi (Ganoderma lucidum) in gout. Prof Amin Kamali provides an enzyme analysis of Agaricus blazei biomass which explains how the mushroom supports the immune system.

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October'04

In this edition, we address the hepato-protective effect of Cordyceps sinensis in liver damage and how Cordyceps could inhibit hepatic fibro genesis derived from chronic liver injury , retard the development of cirrhosis and notably improve liver function. Dr Celia Santos outlines a study in which Cordyceps sinensis supplementation (3 g per day for 90 day) is provided to fourteen (14) patients with alcoholic fatty livers and the reduction in their liver enzyme levels was compared to a control group who only practiced abstinence. Professor Amin Karmali provides a comparative analysis of those enzymes responsible for detoxification in four mushrooms, Corolus versicolor, Cordyceps sinensis, Ganoderma lucidum (Reishi) and Grifola frondosa (Maitake). Dr Girao Bastos, a leading Portuguese professor in veterinarian medicine, provides three clinical cases on the application of Coriolus versicolor in: Cat with FELV, Dog with abdominal tumor and cat with fibro sarcoma in hip.

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