Cultivation Process of Blazei-MRL™
Mycology Research Laboratories Ltd.´s Agaricus blazei powder contains both mycelium and primordia (young fruit body) cultivated into a biomass that is grown on a sterilised (autoclaved) substrate in California.
This cultivation process ensures the powder complies with the EU regulation 1881/2006 for contamination of pesticides and heavy metals.
The cultivation system is proprietary, allowing for standardised production of Agaricus blazei.
Mycelium biomass of mushrooms offers a mixture of many co-operating and co-related healthful bioavailable ingredients prepared by nature itself – it is thus a truly pure natural product.
Mushrooms spend more than 90% of their life cycle in the mycelium. Since mushrooms cannot produce their own energy through photosynthesis, the mycelium must be able to actively obtain or produce extracellular compounds and metabolites that promote the longevity and vitality of the living mushroom. These properties lie behind the high enzymatic activity of the mycelium, which stays preserved in the carefully processed MRL products.
Manufacturing Process of Blazei-MRL™ in tablets presentations
The Agaricus blazei tablets are processed under FSSC 22000 standards in the Netherlands. This ensures that each tablet contains 500 mg of the standardised Agaricus blazei product. The tablets are film coated to protect them from moisture, thus preserving the quality of the product and ensuring a long shelf life.
After passing quality control testing the tablets are released for use. The choice of additives used in manufacture renders these tablets suitable for Kosher or vegetarian use.
Manufacturing Process of Blazei-MRL™ in powder presentations
The fungal biomass Agaricus blazei comprises Blazei-MRL is certified 100% Organic in the United States (California) by Quality Assurance International and recognized as organic by the UK Organic Food Federation.
Chemical and Biological Properties *
Agaricus blazei* Content per gram of biomass (in the absence of Proteolytic Enzymes)
| Cytochrome P-450 | 0.45 nmoles |
| Cytochrome P-450 reductase | 8.90 mU |
| Xylanase | 12.80 U |
| Celulase | 0.38 U |
| Amyloglucosidase | 0.80 U |
| Protein bound polysacharides | 87.6 mg |
| Proteins | 5.16 mg |
| Reducing sugars | 20.38 mg |
| Superoxide dismutase (SOD) | 275.0 U |
| Protease | 11.2 U |
Blazei-MRL –Enzyme activity (U/500 mg Biomass)**
| Superoxide dismutase (SOD) | 143.5 103 U |
| NADPH (Cyt. "P-450" reductase) | 7,500 uM |
| GSH Reductase | 510.0 U |
| Catalase | 996.5 U |
| Laccase | N/A |
| Tyrosinase | 6849 U |
| Peroxidase | N/A |
* Agaricus blazei supplied by Mycology Research Laboratories Ltd.
** Cornelius C. e tal “ Comparative Enzyme Analysis of Polyporus umbellatus, Agaricus blazei, Pleurotus osteratus and Hericium erinaceus” pp 5, Clinical Journal of Mycology, 7;2009 Vol II.