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Besides nutritional properties, mushrooms have attracted market attention because they are a potential source of bioactive compounds able to perform several functions in organisms with benefits for consumer health. In recent years Coriolus versicolor aroused interest among researchers because of the bioactive properties demonstrated.
Polysaccharopeptide (PSP) and polysaccharopeptide Krestin (PSK) have shown to be useful adjuncts to the therapy of cancer; these polysaccharides from C. versicolor have also shown prebiotic activity, stimulating the growth of probiotic bacteria. This review article highlights the health-promoting potential of several mushroom species with special emphasis on C. versicolor.

(1) Universidade Católica Portuguesa, CBQF - Centro de Biotecnologia e Química Fina – Laboratório Associado, Escola Superior de Biotecnologia, Rua Arquiteto Lobão Vital, Apartado 2511, 4202-401 Porto, Portugal

(2) Centro de Investigación en Recursos Naturales y Sustentabilidad (CIRENYS), Universidad Bernardo O’Higgins, Fábrica N∘ 1990, Segundo Piso, Santiago, Chile

(3) CEIL, Lúrio University, Marrere, Nampula, Mozambique

Journal of Food and Nutrition Research. Vol. 4, No. 12, 2016, pp 773-781

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Archives of Environmental Health, August 2003 (Vol. 58 (No.8 )). Reprinted with permission of the Helen Dwight Reid Educational Foundation. Published by Heldref Publications, 1319 18th Street, NW, Washington, DC 20036-1802. Copyright � (2004).

In this article Dr. Monro points discusses how 20% of all cancers are triggered by viral infections. Dr. Monro outlines that having provided 30 Chronic Fatigue Syndrome patients Coriolus-MRL supplementation over eight weeks, there were significant improvements in the overall immune systems of the majority of the patients and that Coriolus supplementation could be utilized as a preventative immunutrition for those patients with such viral conditions that could develop into more serious oncological conditions i.e. HPV infection or Epstein Barr infection. Dr. Monro also outlines that Coriolus supplementation not only increases Natural Killer cell activity by 35%, but may also play a role in facilitating intercellular communication, thereby allowing the immune system to operate more effectively.

For more information on Heldref Publications and the Archives of Environmental Health, see the following link

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This study of increasing Coriolus versicolor supplementation (4.5 grams per day to 13.0 grams per day over a 90 day period) measures the impact of such supplementation on telomerase activity, interleukin 5, interleukin 12 and Tumour Necrosis Factor Beta over 120 days. Results were a significant decrease in teleomerase and interleukin-12 activity, followed by a significant increase in interleukin-5 activity within 120 days.

Presented at the 5th International Symposium on Mushroom Nutrition, University of Westminster, June 14th, 2002.