In this article, Professor Vittorio Calabrese explains the role that the mushrooms Coriolus versicolor and Hericium erinaceus may play in inhibiting the progression of diseases related to oxidative stress such as dementia or early Alzheimer's disease. The role of this mushrooms comes from upregulating LXA4 a protein in the brain cells membrane that will stimulate certain systems within our body to reduce these oxidative species.