The main outcome was to study the mean rate of change in Natural Killer Cell Activity in patients who have undergone conventional breast cancer protocol: chemotherapy followed by radiotherapy in which there is a subseqent decrease in Natural Killer Cell Activity. The study was funded by CTRF and was halted as naturopaths were unable to recruit patients for the study. The attachments outline the rational for the study along with timeline.
Download the CTRF Clinical Study, click here.
Download the CTRF Clinical Timeline, click here.
Clinical Articles
The following section outlines the clinical papers, posters and proposals that refer to the clinical use of MRL mushroom nutrition products. This information is for healthcare practitioners only and should not be provided to members of the general public.
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Clinical articles
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Neuroprotective Effects of Mushroom Biomass Digestive Fractions and Gut Microbiota Metabolites in Microglial and Caenorhabditis elegans Models of Neurodegeneration
Helena Araújo-Rodrigues 1,2 , Lidia Garzón-García 3 Freni K. Tavaria 1 , Celestino Santos-Buelga 3 , Ana Sofia Salsinha 1 , João Bettencourt Relvas 2,4 , Ana M.González-Paramás 3 and Manuela E.Pintado1,* -
Characterization of Children with Intellectual Disabilities and Relevance of Mushroom Hericium Biomass Supplement to Neurocognitive Behavior
Plamen Dimitrov 1,*, Alexandra Petrova 2, Victoria Bell 3,4 and Tito Fernandes 5 -
Bioaccessibility and Bioavailability of Bioactive Compounds from Mushroom Biomass Following in vitro Gastrointestinal Digestion presented at the CIPCA 2025 X International Conference on Food Proteins and Collides June 16-18, 2025 in Porto Portugal.
Helena Araújo-Rodrigues, Manuela Machado, João B. Relvas , Freni K. Tavaria, Manuela Pintado -
Neuroprotective Effects of Mushroom Biomass: Impact of Serum-Available and Gut Microbiota Metabolites in Caenorhabditis elegans Models of Alzheimer’s Disease. Presented on June 13th at the XXIII EURO FOODCHEM 2025 Conference in Bratislava, Slovakia
Helena Araújo-Rodrigues,Lidia Garzón-García, João B. Relvas, Freni K. Tavaria, Celestino Santos-Buelga, Ana M. González-Paramás, and Manuela E. Pintado