While most research studies focus on the polysaccharide fractions of mushroom-fruiting bodies, this study investigates the neuroprotective potential of mushroom biomass (MB) from Trametes versicolor, Hericium erinaceus, and Pleurotus ostreatus considering the possible synergistic effects of different macromolecules found both in the total mushroom and fruiting bodies.
The neuroprotective potential of serum-available fractions and key gut microbiota-derived metabolites were evaluated in transgenic Caenorhabditis elegans models of Alzheimer’s disease by analyzing chemotactic behavior and paralysis onset.
The mushroom biomass used in this study were supplied by Mycology Research Laboratories Ltd.
Clinical Articles
The following section outlines the clinical papers, posters and proposals that refer to the clinical use of MRL mushroom nutrition products. This information is for healthcare practitioners only and should not be provided to members of the general public.
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Clinical articles
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Neuroprotective Effects of Mushroom Biomass Digestive Fractions and Gut Microbiota Metabolites in Microglial and Caenorhabditis elegans Models of Neurodegeneration
Helena Araújo-Rodrigues 1,2 , Lidia Garzón-García 3 Freni K. Tavaria 1 , Celestino Santos-Buelga 3 , Ana Sofia Salsinha 1 , João Bettencourt Relvas 2,4 , Ana M.González-Paramás 3 and Manuela E.Pintado1,* -
Characterization of Children with Intellectual Disabilities and Relevance of Mushroom Hericium Biomass Supplement to Neurocognitive Behavior
Plamen Dimitrov 1,*, Alexandra Petrova 2, Victoria Bell 3,4 and Tito Fernandes 5 -
Bioaccessibility and Bioavailability of Bioactive Compounds from Mushroom Biomass Following in vitro Gastrointestinal Digestion presented at the CIPCA 2025 X International Conference on Food Proteins and Collides June 16-18, 2025 in Porto Portugal.
Helena Araújo-Rodrigues, Manuela Machado, João B. Relvas , Freni K. Tavaria, Manuela Pintado -
Chemical Composition of Trametes versicolor, Hericium erinaceus, and Pleurotus ostreatus Mushroom Biomass: Deciphering their Rich α-glucan Composition and Nutritional Value
Helena Araújo-Rodrigues, Manuela Amorim, Clara Sousa, Ana Sofia Salsinha, Sara Marçal, Victor de Freitas, Joao Bettencourt Relvas, Freni K. Tavaria,Manuela E. Pintado. Journal of Food Composition and Analysis 143 (2025) 107612.