(1) Department of Biomedical and Biotechnological Sciences, School of Medicine, University of Catania, Catania, Italy
(2) Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy
(3) Faculty of Veterinary Medicine, Lisbon University, Portugal
(4) Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari, Bari, Italy
(5) Spinal Unit, Emergency Hospital “Cannizzaro”, Catania, Italy
(6) Department of Clinical and Experimental Medicine, School of Medicine, University of Catania, Catania, Italy
This paper discusses the emerging role of lipoxinA4 and inflammasome in neurodegeneration. In addition, the paper outlines the notion that low levels of stress can induce responses that may be protective against the pathogenic processes is a frontier area of neurobiological research focal to understanding and developing therapeutic approaches to neurodegenerative disorders. Herein, we discuss the potential therapeutic role of Coriolus versicolor, a mushroom (Coriolus-MRL), well known in China as Yun Zhi. We propose a potentially innovative treatment for AD and, possibly, other neurodegenerative conditions associated to neuroinflammation.
Clinical Articles
The following section outlines the clinical papers, posters and proposals that refer to the clinical use of MRL mushroom nutrition products. This information is for healthcare practitioners only and should not be provided to members of the general public.
Download PDF
Clinical articles
-
Enhanced complexity of hippocampal dentate gyrus newly-generated neurons in mice following Coriolus versicolor biomass administration
Ana Cristina Rego (1)(4)(11), Elisabete Ferreiro (1)(2)(4), Inês R. Pita (3)(4), Sandra I. Mota (1)(2),(4), Jorge Valero (5)(6) Nuno R Ferreira (7), Carlos A. Fontes-Ribeiro (3)(4), Tito Fernandes (8)(9), Vittorio Calabrese (10), Frederico C. Pereira (3) (4). -
Coriolus versicolor biomass Increases Hippocampal Dentate Gyrus Newly-Generated Neurons Complexity in Mice.
Frederico C. Pereira1)2), Elisabete Ferreiro2)3)4), Inês R. Pita1)2), Sandra I. Mota2)3)4), Jorge Valero5)6) Nuno R Ferreira7), Carlos A. Fontes-Ribeiro1)2), Tito Fernandes8)9), Vittorio Calabrese10), Cristina Rego2)3)11) -
Coriolus versicolor biomass increases dendritic arborization of newly-generated neurons in mouse hippocampal dentate gyrus
Elisabete Ferreiro* (1,2,4), Inês Pita* (3,4), Nuno R. Ferreira (5), Carlos A Fontes-Ribeiro (3,4), Frederico C. Pereira ** (3,4), A. Cristina Rego** (1,4,6) -
Poor cognitive ageing: Vulnerabilities, mechanisms and the impact of nutritional interventions
Sophie Miquel(1), Claire Champ(1), Jon Day (3), Esther Aarts (4), Ben A. Bahr (5), Martijntje Bakker (6), Diána Bánáti (7), Vittorio Calabrese (8), Tommy Cederholm (9), John Cryan (10), Louise Dye (11), Jonathan A. Farrimond (12), Aniko Korosi(13), Sophie Layé (14), Stuart Maudsley (15), Dragan Milenkovico,(16), M.Hasan Mohajeri (17), John Sijben (18), Alina Solomon (19), Jeremy P.E. Spencer (20), Sandrine Thuret (21), Wim Vanden Berghe (22), David Vauzour (23), Bruno Vellas (24), Keith Wesnesy,(25),(26),(27),(28), Peter Willatts (29),
Raphael Wittenberg (30), Lucie Geurts (7),⁎ S.Miquel et al, Ageing Research Review, 42 (2018) 40-55.